WandaVision, the Disney+ Marvel hit has collected four awards including best show at the MTV Movie & TV Awards.
After a year off due to the pandemic, the fan-voted show returned in front of an in-person audience at the Hollywood Palladium in Los Angeles.
The Marvel Comics-inspired mini-series takes place after the events of the 2019 film Avengers: Endgame.
The Netflix teen romance To All The Boys: Always And Forever was named best movie.
In the gender-neutral individual categories, WandaVision star Elizabeth Olsen won best performance in a show for her portrayal of the avenger Wanda Maximoff/Scarlet Witch.
Elsewhere, Scarlett Johansson was covered in slime by her husband, Saturday Night Live comedian Colin Jost, while remotely accepting the generation award.
Sacha Baron Cohen rolled out some of his best-known characters while accepting the comic genius award.
He accepted the prize as the Kazakhstani journalist Borat, before being interrupted by the wannabe gangster Ali G.
Best performance in a movie went to the late Chadwick Boseman for the music drama Ma Rainey's Black Bottom.
The star died last year of bowel cancer aged 43.
Best breakthrough performance was won by Regé-Jean Page for his role in the period drama Bridgerton – Netflix's biggest ever show.
Page is rumoured to be in the running to play the next James Bond.
The MTV Movie & TV Awards 2021 winners in full:
Best movie – To All The Boys: Always And Forever
Best show – WandaVision
Best hero – Anthony Mackie (The Falcon And The Winter Soldier)
Best performance in a show – Elizabeth Olsen (WandaVision)
Best breakthrough performance – Regé-Jean Page (Bridgerton)
Best kiss – Chase Stokes & Madelyn Cline (Outer Banks)
Best comedic performance – Leslie Jones (Coming 2 America)
Best fight – Wanda vs Agatha (WandaVision)
Best duo – Anthony Mackie and Sebastian Stan (The Falcon And The Winter Soldier)
Best villain – Kathryn Hahn (WandaVision)
Most frightening performance – Victoria Pedretti (The Haunting Of Bly Manor)
Best musical moment – Edge Of Great (Julie And The Phantoms)
Best performance in a movie – Chadwick Boseman (Ma Rainey's Black Bottom)
Comic genius – Sacha Baron Cohen
Generation award – Scarlett Johansson
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