Vakatawa has been named to start at outside centre, and will team up with Josua Tuisova in the midfields.
Fijian Drua utility back Isikeli Rabitu is expected to also make his debut and has been named on the bench.
Flying Fijians Acting Head Coach Senirusi Seruvakula have made a few changes to his starting XV that went down to England last week, with Temo Mayanavanua starting at locks, in place of Tevita Ratuva, who has been sideline for this week.
Mayanavanua will partner with Isoa Nasilasila, and Eroni Mawi, Tevita Ikanivere and Mesake Doge make up the front rows.
Pita Gus Sowakula will start at blindside flanker with Lekima Tagitagivalu at openside, and Elia Canakaivata is at number 8.
Frank Lomani returns and will team up with Caleb Muntz in the halves, while Jiuta Wainiqolo and Selestino Ravutaumada are the wings.
Isaiah Armstrong-Ravula is at fullback.
The forward reserves are Sam Matavesi, Livai Natave, Peni Ravai, Mesake Vocevoce and Kitione Salawa while Sam Wye, Rabitu and Salesi Rayasi provide backline cover.
The Flying Fijians will play Scotaland this Sunday at 1.10am.
In other matches, the All Blacks will host Ireland at 7.10am at Eden Park tomorrow, Japan will meet France at 8.40pm, and the Wallabies will face the Italy at 10.10pm.
On Sunday, South Africa will meet Wales at 3.40am, and England will meet Argentina at 7.10am.
