Manu Tuilagi will be on the bench as England name an unchanged starting 15 for their game against Six Nations title rivals Wales.
The Samoan born and Leicester centre has not played for England since June 2014 because of a groin injury and disciplinary issues.
Coach Eddie Jones says Tuilagi trained well this week and he is pleased with what he has seen.
England play Wales at 4am this Sunday. In other matches, Ireland play Italy at 1.30am Sunday while Scotland play France at 3am on Monday.
