Real Madrid could be without Isco, Raphael Varane, Gareth Bale and Keylor Navas for Thursday's Champions League clash with Tottenham.
Coach Zinedine Zidane has suggested Bale could recover in time.
Madrid and Tottenham are level on seven points each in Champions League Group H and a win for either side will guarantee their place in the last 16.
Real Madrid face Tottenham in the Championship League at 7.45am Thursday.
