The Brumbies have won 10 straight games at home after dispatching the Melbourne Rebels last night.
The dominant hosts triumphed 39-26 to lead the Australia conference early in round two.
The Brumbies scored four unanswered tries in the opening 28 minutes to leave the Rebels playing catch up all night at Canberra Stadium.
Frank Lomani scored a try for the Rebels in the 78th minute.
The Brumbies are chasing their record of 13 straight wins at home, a sequence they established in 1998.
The Crusaders take on the Chiefs at 6.05 tonight while the Blues battle the Waratahs at 8.15 tonight.
The Lions will play the Reds at 1.05am tomorrow while the Stormers and the Bulls play at 3.15am tomorrow and the Hurricanes will take on the Jaquares at 9.40am tomorrow.
Brumbies 39 (Tom Banks, Thomas Cusack, Folau Fainga'a, Solomone Kata, Irae Simone, Tom Wright tries Noah Lolesio 3 cons drop goal) Rebels 26 (Angus Cottrell 2, Dane Haylett-Petty, Frank Lomani tries Lomani 2, Matt To'omua cons) HT: 24-7
