Winger Malelili Satala, son of former Fiji International Apolosi Satala, will make his debut in an Edinburgh side showing six changes for Friday's Champions Cup visit to Bath.
Going into the final round of pool fixtures, Bath lead the way in Group 2 on 11 points, with Edinburgh second on 10 points.
21-year-old Satala takes over from Duhan van der Merwe, who has a calf problem.
Captain Magnus Bradbury is rested for the trip to The Rec, along with Pierre Schoeman, Liam McConnell and Wes Goosen.
Ben Muncaster and Tom Dodd start in the back-row, while Harry Paterson returns from injury to start at full-back.
Ewan Ashman takes over from Harri Morris at hooker and Piers O'Conor slots into the midfield for the injured Matt Currie (hamstring).
Head coach Sean Everitt says they are excited to give Maleli his chance, as he is a player with genuine X-factor and has worked hard for the opportunity.
Edinburgh: Paterson, Graham, O'Conor, Lang, Satala, Thompson, Vellacott (capt); Whitcombe, Ashman, Blyth-Lafferty, Hunter-Hill, Young, Dodd, Douglas, Muncaster.
Replacements: Morris, Jones, Hill, McVie, Boyle, Shiel, Healy, Brown.
Source: BBC News
